PDF | It is unclear whether decompressive craniectomy improves the functional outcome in patients with severe traumatic brain injury and. The Decompressive Craniectomy in Diffuse Traumatic Brain Injury or DECRA trial was the first neurosurgical randomized controlled trail that sought to answer. BACKGROUND It is unclear whether decompressive craniectomy improves the functional outcome in patients with severe traumatic brain injury and refractory.

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Decompressive craniectomy in diffuse traumatic brain injury.

In addition, the main similarity between the results of these two studies was that DC reduced ICP effectively but increase larger proportion of survivors in the vegetative state and severe disability significantly.

It is a descriptive, retrospective study with a relatively small number of patients, conducted in a single center, which reduces statistical power. Outcome following evacuation of acute subdural haematomas: Decompressive craniectomy for traumatic intracranial hypertension: Would decompressive craniectomy really bring the hope to severe traumatic brain injury?

A preinformed consent in craiectomy uniform format was taken from all these patients for being a part of this study and their details to be published.

Decompressive Craniectomy in Diffuse Traumatic Brain Injury: The DECRA Trial – Oxford Medicine

Qualified, late specialism training. Kjellberg RN, Prieto A. The aim of this retrospective study was to analyze the clinicoradiological factors associated with the prognosis of severe TBI in patients undergoing DC.

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Morbidity, mortality, and operative timing. Comment in N Engl J Med.

No long-term follow-up of patients was done. Table 11 Outcome as per Glasgow outcome scale in patients with respect to Marshall computed tomography grading. Although barbiturates are included in level II recommendations of TBI guideline 5a Cochrane systematic review concluded that barbiturates may reduce ICP but do not reduce mortality or improve outcome in severe TBI survivors METHODS From December through Aprilwe randomly assigned adults with severe diffuse traumatic brain injury and intracranial hypertension that was refractory to first-tier therapies to undergo either bifrontotemporoparietal decompressive craniectomy or standard care.

Complications of decompressive craniectomy for traumatic brain injury. With increased severity of disease, elderly patients and those on aspirin or other anticoagulants complications decomptessive decompressive craniectomy have been found to be increased. Population clock Sensory and Motor Systems.

Decompressive Craniectomy in Diffuse Traumatic Brain Injury: An Industrial Hospital Study

Past experience and current developments Andrew I. Do long-term results justify decompressive craniectomy after severe traumatic brain injury?

Clinical trials in traumatic brain injury: Sign in via your Institution. The other question is what other indicators need established in order to evaluate DC timing. Our study population is heterogeneous in terms of their clinical characteristics, indications, and opportunity for DC, and technique used, which limits the precision of our results. Second-line therapies are started when these measures fail to control high ICP.

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Decompressive craniectomy in diffuse traumatic brain injury. – Semantic Scholar

Mortality was more in patient of GCS 4—6 Number of cases with respect to timing of surgery early if done within 24 h and late if done after 24 h.

Search within my specialty: Clinical Pharmacology and Therapeutics. Oxford Textbooks in Anaesthesia. Oxford Textbooks brai Public Health. N Engl J Med.

Decompressive craniectomy in diffuse traumatic brain injury. In adults with severe diffuse traumatic brain injury and refractory intracranial hypertension, early bifrontotemporoparietal decompressive craniectomy decreased intracranial pressure and the length of stay in the ICU but was associated with more unfavorable outcomes.

Stephen Honeybul Evidence-based medicine Child and Adolescent Psychiatry.